Awards, Patents and Publications for Dr Davendra Segara


Segara D.
Studies of Retinoic Acid Signalling In Pancreatic Cancer
UNSW 2007


Methods of Diagnosis and Prognosis in Pancreatic Cancer
Biankin AV, Henshall SM, Segara D and Sutherland RL
International Patent Application PCT/AU2004/000194


St Vincent’s Clinic Foundation Travelling Scholarship

Australia and Asia Pacific Clinical Oncology Research Development (ACORD)
Workshop Travel Fellowship

National Health And Medical Research Council (NHMRC):
Medical Postgraduate Scholarship

Royal Australasian College Of Surgeons:
John Loewenthal Research Scholarship

St Vincent’s Clinic Foundation K & A Collins
Cancer Research Grant


Wu SZ, Roden DL, Wang C, Holliday H, Harvey K, Cazet AS, Murphy KJ, Pereira B, Al-Eryani G, Bartonicek N, Hou R, Torpy JR, Junankar S, Chan CL, Lam CE, Hui MN, Gluch L, Beith J, Parker A, Robbins E, Segara D, Mak C, Cooper C, Warrier S, Forrest A, Powell J, O’Toole S, Cox TR, Timpson P, Lim E, Liu XS, Swarbrick A.
Stromal cell diversity associated with immune evasion in human triple-negative breast cancer.
EMBO J. 2020 Oct 1;39(19):e104063. Epub 2020 Aug 13. doi: 10.15252/embj.2019104063.

Portman N, Milioli HH, Alexandrou S, Coulson R, Yong A, Fernandez KJ, Chia KM, Halilovic E, Segara D, Parker A, Haupt S, Haupt Y, Tilley WD, Swarbrick A, Caldon CE, Lim E.
MDM2 inhibition in combination with endocrine therapy and CDK4/6 inhibition for the treatment of ER-positive breast cancer.
Breast Cancer Res. 2020 Aug 12;22(1):87. doi: 10.1186/s13058-020-01318-2.

Chen J, Easwaralingam N, Warrier S, Ong A, Carson EK, Mak C, Snook K, Middleton K, Parker A, Palmieri C, Spillane A, Mann GB, Lim E, Segara D.
Window of opportunity Treatment in Breast Cancer
ANZ J Surg. 2019 Nov 26. doi: 10.1111/ans.15487.

Field AS, Raymond WA, Rickard M, Arnold L, Brachtel EF, Chaiwun B, Chen L, Di Bonito L, Kurtycz DFI, Lee AHS, Lim E, Ljung BM, Michelow P, Osamura RY, Pinamonti M, Sauer T, Segara D, Tse G, Vielh P, Chong PY, Schmitt F.
The International Academy of Cytology Yokohama System for Reporting Breast Fine-Needle Aspiration Biopsy Cytopathology.
Acta Cytol. 2019;63(4):257-273. doi: 10.1159/000499509. Epub 2019 May 21

Chia K, Milioli H, Portman N, Laven-Law G, Coulson R, Yong A, Segara D, Parker A, Caldon CE, Deng N, Swarbrick A, Tilley WD, Hickey TE, Lim E.
Non-canonical AR activity facilitates endocrine resistance in breast cancer.
Endocr Relat Cancer. 2019 Feb 1;26(2):251-264. doi: 10.1530/ERC-18-0333.

Soon PS, Ruban S, Mo HTJ, Lee R, Saliba L, Shah A, Segara D, Yarrow S, Girgis A.
Understanding patient choices regarding breast reconstruction after mastectomy for breast cancer.
Support Care Cancer. 2019 Jun;27(6):2135-2142. doi: 10.1007/s00520-018-4470-0. Epub 2018 Sep 25.

Pennington TE, Enoch JF, Segara D.
Appendicitis diagnosed on positron emission tomography scan: an ‘incidentalitis’.
ANZ J Surg. 2019 Jun;89(6):779-781. doi: 10.1111/ans.14307. Epub 2017 Dec 10.

Selvendran S, Cheluvappa R, Tr Ng VK, Yarrow S, Pang TC, Segara D, Soon P.
Efficacy of harmonic focus scalpel in seroma prevention after axillary clearance.
Int J Surg. 2016 Jun;30:116-20. doi: 10.1016/j.ijsu.2016.04.041. Epub 2016 Apr 29.

Chang LY, Hargreaves W, Segara D, Moisidis E.
Experience in dermomyofascial pouch coverage of immediate implants following skin sparing reduction mastectomy.
ANZ J Surg. 2013 Mar; 83(3):135-8. doi: 10.1111/j.1445-2197.2012.06313.x. Epub 2012 Dec 17

Colvin EK, Susanto JM, Kench JG, Ong VN, Mawson A, Pinese M, Chang DK, Rooman I, O’Toole SA, Segara D, Musgrove EA, Sutherland RL, Apte MV, Scarlett CJ, Biankin AV
Retinoid signaling in pancreatic cancer, injury and regeneration.
PLoS One. 2011;6(12):e29075. Epub 2011 Dec 29.

Javid S, Segara D, Lotfi P, Raza S, Golshan M.
Can breast MRI predict axillary lymph node metastasis in women undergoing neoadjuvant chemotherapy.
Ann Surg Oncol. 2010 Jul;17(7):1841-6. Epub 2010 Feb 9

Murphy NC, Biankin AV, Millar EK, McNeil CM, O’Toole SA, Segara D, Crea P, Olayioye MA, Lee CS, Fox SB, Morey AL, Christie M, Musgrove EA, Daly RJ, Lindeman GJ, Henshall SM, Visvader JE, Sutherland RL.
Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.
Int J Cancer. 2010 Mar 15;126(6):1445-53.

Peters AA, Buchanan G, Ricciardelli C, Bianco-Miotto T, Centenera MM, Harris JM, Jindal S, Segara D, Jia L, Moore NL, Henshall SM, Birrell SN, Coetzee GA, Sutherland RL, Butler LM, Tilley WD.
Androgen receptor inhibits estrogen receptor-alpha activity and is prognostic in breast cancer.
Cancer Res. 2009 Aug 1;69(15):6131-40. Epub 2009 Jul 28.

Pinese M, Scarlett CJ, Kench JG, Colvin EK, Segara D, Henshall SM, Sutherland RL, Biankin AV.
Messina: a novel analysis tool to identify biologically relevant molecules in disease.
PLoS One. 2009;4(4):e5337. Epub 2009 Apr 28.

Biankin AV, Kench JG, Colvin EK, Segara D, Scarlett CJ, Nguyen NQ, Chang DK, Morey AL, Lee CS, Pinese M, Kuo SC, Susanto JM, Cosman PH, Lindeman GJ, Visvader JE, Nguyen TV, Merrett ND, Warusavitarne J, Musgrove EA, Henshall SM, Sutherland RL; NSW Pancreatic Cancer Network.
Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer.
Gastroenterology. 2009 Aug;137(2):558-68, 568.e1-11. Epub 2009 Apr 16.

Tan EY, Yan M, Campo L, Han C, Takano E, Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, O’Toole SA, McNeil CM, Crea P, Segara D, Sutherland RL, Harris AL, Fox SB.
The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy.
Br J Cancer. 2009 Jan 27;100(2):405-11.

Murphy NC, Scarlett CJ, Kench JG, Sum EY, Segara D, Colvin EK, Susanto J, Cosman PH, Lee CS, Musgrove EA, Sutherland RL, Lindeman GJ, Henshall SM, Visvader JE, Biankin AV.
Expression of LMO4 and outcome in pancreatic ductal adenocarcinoma.
Br J Cancer. 2008 Feb 12;98(3):537-41. Epub 2008 Jan 29.

Segara D, Krop I.E, Garber J.E, Winer E, Harris L, Bellon J.R, Birdwell R, Lester S, Lipsitz S, Iglehart J.D, and Golshan M
Does MRI Predict Pathologic Tumor Response in Women With Breast Cancer Undergoing Preoperative Chempotherapy?
J Surg Oncol. 2007 Nov 1;96(6):474-80

Pasca di Magliano M, Biankin AV, Heiser PW, Cano DA, Gutierrez PJ, Deramaudt T, Segara D, Dawson AC, Kench JG, Henshall SM, Sutherland RL, Dlugosz A, Rustgi AK, Hebrok M.
Common activation of canonical wnt signaling in pancreatic adenocarcinoma.
PLoS ONE. 2007 Nov 7;2(11):e1155.

Chan J.S, Segara D and Nair P
Measurement of Cardiac Output using a Non Invasive Continuos Wave Doppler Device vs. The Pulmonary Artery Catheter; A Comparative Study.
Crit Care Resusc. 2006 Dec;8(4):309-14

Skalicky DA, Kench JG, Segara D, Coleman MJ, Sutherland RL, Henshall SM, Musgrove EA, Biankin AV.
Cyclin E Expression and Outcome in Pancreatic Ductal Adenocarcinoma
Cancer Epidemiology Biomarkers Prev. 2006 Oct;15(10):1941-7

Ting CCA, Jones G, Segara D and Chisolm D.
Rapid Reversal of the Chylomicronaemia Syndrome with Conservative Management.
Intern. Med. J. 2006:36(10) 682-683.

Sum EYM., Segara D, Duscio B, Bath ML, Field A.S, Sutherland RL., Lindeman G.J, Visvader JE.
Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer.
Proc Natl Acad Sci U S A. 2005 May 24;102(21):7659-64.

Segara D, Biankin AV, Kench JG, Langusch CC, Dawson AC, Skalicky DA, Gotley DC, Coleman MJ, Sutherland RL, Henshall SM.
Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia.
Clin Cancer Res. 2005 May 1;11(9):3587-96.

Clancy JL, Henderson MJ, Russell AJ, Anderson DW, Bova RJ, Campbell IG, Choong DY, Macdonald GA, Mann GJ, Nolan T, Brady G, Olopade OI, Woollatt E, Davies MJ, Segara D, Hacker NF, Henshall SM, Sutherland RL, Watts CK
EDD, the human orthologue of the hyper plastic discs tumour suppressor gene, is amplified and overexpressed in cancer.
Oncogene. 2003 Aug 7;22(32):5070-81.


Segara D, Kench JG Eggleton SA Coleman M.J., Sutherland R.L., Henshall S.M. and Biankin A.V
Novel Role of Retinoic Acid in Pancreatic Cancer.
ANZ Journal of Surgery 2005 October: 75(10) A135

Dawson AC, Segara D, Biankin AV, Kench JG, Sutherland RL.
Validation of Immunohistochemistry as a scoring test: How accurate are Beta-Catenin and SFRP4 diagnostically?
ANZ Journal of Surgery 2005 October: 75(10) A137

Dawson AC, Horvath LG, Segara D, Biankin AV, Kench JG, Sutherland RL, Henshall SM
Pancreatic Cancer and the Wnt Pathway.
ANZ Journal of Surgery 2003 May supplement: 73; A108.

Segara D, Biankin A.V. Coleman M.J., Sutherland R.L. and Henshall S.M.
A gene based approach to the identification of novel genes in the development and progression of Pancreatic Cancer by transcript profiling.
ANZ Journal of Surgery 2003 May supplement: 73; A108.

+ > 10 published abstracts as part of conference proceedings.


Segara D.
Book Review: Breast Cancer
“Hunt K, Robb G., Strom E and Ueno N”: Today’s Life Science
October 2002